کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5267841 | 1385348 | 2015 | 4 صفحه PDF | دانلود رایگان |
Oxidation of benzylic alcohol to ketone or aldehyde is one of the most challenging reactions in terms of green chemistry. We report herein that employing H2O2, catalytic amount of Brâ and acid in continuous-flow system to realize oxidation of benzylic alcohols with broad substrate scope and high selectivity. More importantly, no over oxidation to acid was obtained and it showed higher selectivity to 2° hydroxyl groups rather than 1°.
Oxidation of benzylic alcohol to ketone or aldehyde is one of the most challenging reactions in terms of green chemistry. We report herein that the oxidation of benzylic alcohols with broad substrate scope and high selectivity is realized by employing H2O2, catalytic amount of Brâ and acid in continuous-flow system. More importantly, no over oxidation to acid was obtained and it showed higher selectivity to 2° hydroxyl groups rather than 1°.69
Journal: Tetrahedron Letters - Volume 56, Issue 44, 28 October 2015, Pages 5973-5976