کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5268750 1385371 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
An efficient one-pot three-component synthesis of functionalized pyrimido[4,5-b]quinolines and indeno fused pyrido[2,3-d]pyrimidines in water
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
An efficient one-pot three-component synthesis of functionalized pyrimido[4,5-b]quinolines and indeno fused pyrido[2,3-d]pyrimidines in water
چکیده انگلیسی

A simple, efficient, and high yielding one-pot protocol for the synthesis of pyrimido[4,5-b]quinolines and indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidines has been developed by three-component domino coupling of 6-amino-1,3-dimethyluracil, aldehydes, and cyclic 1,3-diketones in ecofriendly solvent water promoted by PTSA. The protocol avoids the use of expensive catalysts, toxic solvents, and chromatographic separation. The generality and functional tolerance of this convergent and environmentally benign method is demonstrated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 53, Issue 4, 25 January 2012, Pages 399-402
نویسندگان
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