A facile synthesis of N-Z/Boc-protected 1,3,4-oxadiazole-based peptidomimetics employing peptidyl thiosemicarbazides

Synthesis of 1,3,4-oxadiazole containing peptidomimetics from the corresponding dipeptidyl thiosemicarbazides is reported. Further, the protocol is extended for the synthesis of orthogonally protected 1,3,4-oxadiazole tethered mimetics as well.