کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5268990 1385378 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Highly regioselective synthesis of glycospiro heterocycles through 1,3-dipolar cycloaddition reaction
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Highly regioselective synthesis of glycospiro heterocycles through 1,3-dipolar cycloaddition reaction
چکیده انگلیسی
A highly regio-selective synthesis of novel glycospiropyrrolidines has been accomplished by 1,3-dipolar cycloaddition (1,3-DC) reaction. A unique dipolarophile derived from galactose has been reacted with azomethine ylide generated from 1,2-diketones and secondary aminoacids to give the corresponding spiro glycoheterocycles in good yields. The structures were assigned by 2D NMR spectra and the regio- and stereochemical outcome of the cycloadducts was established by a single crystal X-ray analysis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 51, Issue 34, 25 August 2010, Pages 4538-4542
نویسندگان
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