Makomotines A to D from Makomotake, Zizania latifolia infected with Ustilago esculenta

Four novel compounds, makomotines A to D (1-4), along with two known ones (5, 6) were isolated from Makomotake, Zizania latifolia infected with Ustilago esculenta. The structures were determined or identified by the interpretation of spectroscopic data. Compound 1 suppressed the formation of osteoclast without toxicity.