کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5269848 1385399 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
New polyhydroxy sterols from the marine sponge Callyspongia fibrosa (Ridley & Dendly)
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
New polyhydroxy sterols from the marine sponge Callyspongia fibrosa (Ridley & Dendly)
چکیده انگلیسی
Four new polyhydroxylated sterols and two known sterols are isolated from marine sponge Callyspongia fibrosa collected from the Gulf of Mannar, western Bay of Bengal (India). The sterols contain 3β,6β-dihydroxy system and 25-O-acetate as common features. The hydroxylation pattern is without a precedent in sponge sterols although known in coral sterols. The major steroid 4a showed antimalarial activity against Plasmodium falciparum on the chloroquine-resistant stain better than on the chloroquine-sensitive strain.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 51, Issue 27, 7 July 2010, Pages 3583-3586
نویسندگان
, , , , , ,