Synthesis of phenothiazine-corrole dyads: the enhanced DNA photocleavage properties

Three new phenothiazine-corrole dyads were prepared by the reaction of phenothiazine-10-carbonyl chloride and mono-hydroxyl triaryl corrole in the presence of DBU. As compared to corrole monomer, these phenothiazine-corrole dyads exhibit significant enhanced DNA photocleavage activity as compared to corrole monomer precursors.

Three new phenothiazine-corrole dyads were prepared by the reaction of phenothiazine-10-carbonyl chloride and mono-hydroxyl triaryl corrole in the presence of DBU. These phenothiazine-corrole dyads exhibit significant enhanced DNA photocleavage activity as compared to corrole monomer precursors.