کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5270506 | 1385418 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Microwave assisted rapid, catalyst-free, and efficient synthesis of a new class of diversely functionalized 3-hydroxy-2-oxindole scaffolds under aqueous reaction media
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Microwave assisted rapid, catalyst-free, and efficient synthesis of a new class of diversely functionalized 3-hydroxy-2-oxindole scaffolds under aqueous reaction media Microwave assisted rapid, catalyst-free, and efficient synthesis of a new class of diversely functionalized 3-hydroxy-2-oxindole scaffolds under aqueous reaction media](/preview/png/5270506.png)
چکیده انگلیسی
An efficient and rapid synthesis of a new class of diversely functionalized 3-substituted, 3-hydroxy-2-oxindoles scaffolds in catalyst-free conditions is described by the reaction of 1,3-diketone with isatins under microwave irradiation in aqueous medium. The generality of the reaction to afford the γ regioselective aldol addition products is well demonstrated by screening different structurally varied 1,3-diketone nucleophiles as well as isatin electrophiles. Simple reaction condition, good isolated yield of the product, and environmentally benign medium are attractive features of the present protocol.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 55, Issue 15, 9 April 2014, Pages 2459-2462
Journal: Tetrahedron Letters - Volume 55, Issue 15, 9 April 2014, Pages 2459-2462
نویسندگان
Pramod B. Thakur, K. Sirisha, A.V.S. Sarma, Harshadas M. Meshram,