Oxidative conversion of amines into benzoxazoles using hydrogen transfer catalysis

Benzoxazoles are synthesised directly by oxidative condensation of primary and secondary amines with o-aminophenols under hydrogen transfer catalysis. The optimal system utilises 1 mol % of the Shvo catalyst, with dimethoxybenzoquinone as the hydrogen-accepting terminal oxidant.

Benzoxazoles are synthesised directly by oxidative condensation of o-aminophenols with amines using hydrogen transfer catalysis.