An inexpensive cyclodiphosphazane as an efficient ligand for the palladium-catalyzed amination of aryl bromides and chlorides

An economic and novel ligand, cyclodiphosphazane [ClPN(t-Bu)]2 (1), was introduced in the palladium-catalyzed amination of unactivated aryl halides. The catalyst allows for the amination of aryl chlorides and bromides with secondary cyclic amines and anilines in good yields.

A new catalytic system for the C–N bond formation between aryl bromides/chlorides with amines, using Pd2dba3 and an inexpensive cyclodiphosphazane (1) as a ligand, is presented.Figure optionsDownload as PowerPoint slide