One-pot Suzuki-Miyaura cross-coupling followed by reductive monoalkylation of the resulting nitro biaryl system utilizing Pd/C as catalyst

Conditions for one-pot Suzuki-Miyaura cross-coupling between aryl boronic acids and bromo-nitrobenzene followed by reductive monoalkylation of the nitro functionality of the biaryl cross-coupling product utilizing hydrogen over Pd/C as the catalyst and aldehydes as alkylation agent are described.