Practical and reliable synthesis of dialkyl N-arylphosphoramidates with nitroarenes as substrates

A new single-step transformation of readily available nitroarenes with trialkyl phosphites, which can be performed both under thermal and microwave conditions, delivers dialkyl N-arylphosphoramidates in good yields and short reaction times.

The efficient synthesis of dialkyl N-arylphosphoramidates by reaction of nitroarenes with trialkyl phosphites under thermal as well as under microwave conditions is reported.