کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5271753 1385447 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mild conversion of propargylic alcohols to α,β-unsaturated enones in ionic liquids (ILs); a new 'metal free' life for the Rupe rearrangement
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Mild conversion of propargylic alcohols to α,β-unsaturated enones in ionic liquids (ILs); a new 'metal free' life for the Rupe rearrangement
چکیده انگلیسی

A mild and selective transition metal free protocol for the conversion of propargylic alcohols to cyclic and acyclic α,β-unsaturated enones via the Rupe rearrangement is reported. The method utilizes the Brønsted acidic ionic liquid [BMIM-SO3H][OTf] as catalyst and [BMIM][PF6] as solvent and offers the potential for recycling and reuse of the IL solvent. The feasibility to synthesize bicyclic fused cyclopentenone derivatives via a Rupe → Aldol → Nazarov sequence utilizing this protocol has also been demonstrated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 54, Issue 46, 13 November 2013, Pages 6258-6263
نویسندگان
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