Novel synthesis of indolylquinoline derivatives via the C-alkylation of Baylis–Hillman adducts

A new and simple method for the C-alkylation of indoles by various Baylis–Hillman adducts and the one-pot reductive cyclization of C-alkylated indole derivatives generated from 2-nitro-Baylis–Hillman adduct to form indolylquinoline derivatives is described.

A new and simple method for the C-alkylation of indoles by various Baylis–Hillman adducts and the one-pot reductive cyclization of C-alkylated indole derivatives generated from 2-nitro-Baylis–Hillman adduct to form indolylquinoline derivatives is described.Figure optionsDownload as PowerPoint slide