کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5272177 | 1385459 | 2009 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
An expeditious synthesis of cyanohydrin trimethylsilyl ethers using tetraethylammonium 2-(carbamoyl)benzoate as a bifunctional organocatalyst
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: An expeditious synthesis of cyanohydrin trimethylsilyl ethers using tetraethylammonium 2-(carbamoyl)benzoate as a bifunctional organocatalyst An expeditious synthesis of cyanohydrin trimethylsilyl ethers using tetraethylammonium 2-(carbamoyl)benzoate as a bifunctional organocatalyst](/preview/png/5272177.png)
چکیده انگلیسی
Phthalimide and tetraethylammonium hydroxide react via an unusual pathway to afford tetraethylammonium 2-(carbamoyl)benzoate (TEACB) which is of interest as a bifunctional organocatalyst. TEACB (0.5 mol %) was found to catalyze the addition of trimethylsilyl cyanide (TMSCN) to carbonyl compounds under solvent-free conditions at room temperature with very short reaction times. A wide variety of aldehydes and ketones were transformed into the corresponding cyanohydrin trimethylsilyl ethers in high to quantitative yields.
Tetraethylammonium 2-(carbamoyl)benzoate (TEACB) was found to be an effective bifunctional organocatalyst for rapid and clean cyanosilylation of carbonyl compounds under solvent-free conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 50, Issue 28, 15 July 2009, Pages 4063-4066
Journal: Tetrahedron Letters - Volume 50, Issue 28, 15 July 2009, Pages 4063-4066
نویسندگان
Mohammad G. Dekamin, Solmaz Sagheb-Asl, M. Reza Naimi-Jamal,