کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5272643 1385468 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of 6a-hydroxypterocarpans via intramolecular benzoin condensation
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of 6a-hydroxypterocarpans via intramolecular benzoin condensation
چکیده انگلیسی

A novel approach for the syntheses of 6a-hydroxypterocarpans is reported. Its practicality is demonstrated by the synthesis of (±)-glycinol. The main feature is an intramolecular benzoin condensation catalyzed by nucleophilic carbenes to initiate assembly of the benzopyran and establish the 6a-hydroxy center. In addition, a one-pot method was developed to form an epoxide that facilitates subsequent cyclization leading to the benzofuran and direct production of (±)-glycinol.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 54, Issue 31, 31 July 2013, Pages 4121-4124
نویسندگان
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