Direct substitution of propargylic alcohol with oxygen, nitrogen, and carbon nucleophiles catalyzed by molybdenum(VI)

Efficient and direct substitution of propargylic alcohol with a variety of oxygen, nitrogen, and carbon nucleophiles catalyzed by MoO2(acac)2/NH4PF6 system was developed. The functional alkynes were obtained in modest to good yields with this versatile and practical protocol.