'Ligand-free' palladium-catalyzed direct C-H bond oxidative acyloxylation of 2-arylpyridines with aromatic carboxylic acids

A palladium-catalyzed direct C-H bond oxidative acyloxylation of 2-arylpyridines with aromatic carboxylic acids is described. Several 2-arylpyridines derivatives and aromatic carboxylic acids participate in the reaction, providing a series of mono-acyloxylated products in moderate to good yields. Importantly, the reaction can be conducted without using any ligands in a lower temperature.