کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5273385 1385488 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
1-(d-Glucopyranosyl-2′-deoxy-2′-iminomethyl)-2-hydroxybenzene as chemosensor for aromatic amino acids by switch-on fluorescence
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
1-(d-Glucopyranosyl-2′-deoxy-2′-iminomethyl)-2-hydroxybenzene as chemosensor for aromatic amino acids by switch-on fluorescence
چکیده انگلیسی
A glucose based C2-glyco-conjugate, that is, 1-(d-glucopyranosyl-2′-deoxy-2′-imino-methyl)-2-hydroxybenzene (L), has been synthesized in high yield and characterized. Titration of L with all the 20 naturally occurring amino acids resulted in a large fluorescence intensity enhancement only in case of aromatic amino acids, that is., Phe, Trp, His, and Tyr and not with the others. This has been attributed to the initial formation of 1:1 hydrogen bonded complex followed by π-π interactions present between the aromatic moieties of such complexes as demonstrated by absorption and computational methods. Thus L has been able to recognize aromatic amino acids down to 1.5-3 ppm through switch-on fluorescence behavior.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 51, Issue 1, 6 January 2010, Pages 139-142
نویسندگان
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