کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5273706 1385496 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
An efficient and chemoselective Brønsted acidic ionic liquid-catalyzed N-Boc protection of amines
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
An efficient and chemoselective Brønsted acidic ionic liquid-catalyzed N-Boc protection of amines
چکیده انگلیسی

The first report of a Brønsted acidic ionic liquid, 1-methylimidazolium tetrafluoroborate [(HMIm)BF4], catalyzed efficient and chemoselective N-Boc protection of various amines using (Boc)2O is presented. Optically pure amino alcohols and amino acid esters were converted efficiently to their corresponding optically pure N-Boc derivatives. The reported method is mild, solvent-free and has the advantages of both homogeneous and heterogeneous catalysis with high product yields, selectivity and ease of product separation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 49, Issue 16, 14 April 2008, Pages 2527-2532
نویسندگان
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