Enantioselective Henry reaction catalyzed by trianglamine-Cu(OAc)2 complex under solvent-free conditions

Chiral trianglamine-Cu(OAc)2 complex was found to be an efficient catalyst for enantioselective Henry reaction between nitromethane and various aldehydes to provide β-hydroxynitoroalkanes with high enantiomeric excesses under solvent-free conditions.

Trianglamine-Cu(OAc)2 complex was found to be an efficient catalyst for enantioselective Henry reaction between nitromethane and various aldehydes to provide β-hydroxynitroalkanes with high ee under solvent-free conditions.