کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5274620 | 1385515 | 2008 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Brønsted acid promoted imino-ene reactions Brønsted acid promoted imino-ene reactions](/preview/png/5274620.png)
A series of all-carbon olefins react with glyoxylate derived imines in the presence of a phosphonic acid through an ene reaction. The isolation of the α-aminoester products is a clear indication that Brønsted acids efficiently promote the imino-ene reaction with hydrocarbon nucleophiles to deliver functionalized α-aminoesters in good yield. The reaction scope and preliminary mechanistic investigations are discussed.
A series of all-carbon olefins react with glyoxylate-derived imines in the presence of a phosphonic acid through an ene reaction. The isolation of the α-aminoester products is a clear indication that Bronsted acids efficiently promote the imino-ene reaction with hydrocarbon nucleophiles to deliver functionalized α-aminoesters in good yield. The reaction scope and preliminary mechanistic investigations are discussed.
Journal: Tetrahedron Letters - Volume 49, Issue 31, 28 July 2008, Pages 4636-4639