کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5274878 1385520 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Superbase-promoted direct N-carbonylation of pyrrole with carbonic acid diesters
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Superbase-promoted direct N-carbonylation of pyrrole with carbonic acid diesters
چکیده انگلیسی

Carbonic acid diesters have been investigated as carbonylating agents in the direct reaction with pyrrole (HetNH). In the presence of superbases (DBU, P1-t-Bu, BTPP) as catalysts, the heteroaromatic substrate can be N-carbonylated by direct reaction with carbonic acid diesters under not-severe experimental conditions. The carbonylation reaction makes accessible pyrrole N-carbonyl derivatives (HetNC(O)OR, (HetN)2CO) selectively through a simple straightforward way, which offers a safe eco-friendly alternative to the traditional synthetic methods based on hazardous phosgene or phosgene-derivatives.

Organic carbonates have been studied as carbonylating agents in the direct reaction with pyrrole.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 49, Issue 22, 26 May 2008, Pages 3691-3696
نویسندگان
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