MoO2Cl2 as a novel catalyst for Friedel-Crafts acylation and sulfonylation

The use of MoO2Cl2 as a novel catalyst for Friedel-Crafts acylation and sulfonylation is described. A series of aromatic ketones and sulfones were prepared in moderate to good yields using acyl chloride or sulfonyl chloride in the presence of MoO2Cl2 (20 mol %), under solvent-free conditions.

MoO2Cl2 catalyzes the synthesis of aromatic ketones and sulfones in moderate to good yields.