Highly selective anti-Markovnikov addition of thiols to vinyl ethers under solvent- and catalyst-free conditions

A simple and efficient protocol for the anti-Markovnikov addition of thiols to vinyl ethers under solvent- and catalyst-free conditions has been established. A series of thiol ethers containing oxygen atom were obtained with good to excellent yields.

A series of thiol ether containing oxygen atom have been prepared by a simple and efficient anti-Markovnikov addition of thiols to vinyl ethers under solvent- and catalyst-free conditions.