کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5275164 1385527 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Positional chemoselectivity in the Zn(II)-mediated removal of phenol protecting groups
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Positional chemoselectivity in the Zn(II)-mediated removal of phenol protecting groups
چکیده انگلیسی

A protocol was developed for the chemoselective ortho-deprotection of polyphenolic substrates using readily available ZnIIX2 salts. This procedure provides exceptional positional selectivity for the deprotection of phenols that reside adjacent to directing carbonyl functionality in the presence of similar protecting groups at the meta and para positions. Good to excellent yields of the desired free phenols were obtained (⩽96%), and a wide assortment of protecting groups was readily removed under the reaction conditions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 53, Issue 40, 3 October 2012, Pages 5376-5379
نویسندگان
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