The first examples of the enantioselective Heck-Matsuda reaction: arylation of unactivated cyclic olefins using chiral bisoxazolines

Successful enantioselective Heck-Matsuda arylations were accomplished for the first time using chiral bisoxazolines as ligands. Enantioselective Heck arylations were performed with several cyclic nonactivated olefins to provide the Heck products in 63-96% isolated yields and in enantiomeric excesses of 54% up to 84%.