A palladium-catalyzed one-pot procedure for the regioselective dimerization and cyanation of indoles

A one-pot method for the regioselective dimerization and cyanation of indoles has been developed. The reaction uses safe and nontoxic K4[Fe(CN)6]·3H2O as the cyanating agent which introduces selectively a cyano group into the 3-position of biindoles with high efficiency.

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