Development of a convenient synthetic route to aminochromenes via Buchwald C-N coupling

A convenient new synthetic route to p-aminophenylaminobenzo- and naphthopyrans was developed via palladium-catalyzed C-N coupling. It was demonstrated that novel targeted aminoderivatives reveal photochromic properties. The structure of intermediate p-nitrophenylaminochromenes was confirmed by X-ray crystallographic analysis.

A convenient new synthetic route to p-aminophenylaminobenzo- and naphthopyrans was developed via palladium-catalyzed C-N coupling. It was demonstrated that novel targeted aminoderivatives reveal photochromic properties. The structure of intermediate p-nitrophenylaminochromenes was confirmed by X-ray crystallographic analysis.