A rapid stereoselective C-glycosidation of indoles and pyrrole via indium trichloride promoted reactions of glycosyl halides

Various C-glycosyl indoles and pyrroles were synthesized within a few minutes through coupling acetobromo sugars with suitably substituted indoles and pyrrole in the presence of catalytic amounts of InCl3 at room temperature. Most of the glycosylations proceeded with a high stereoselectivity.