Synthesis of β,β-disubstituted-α-methylene-γ-butyrolactones via the regioselective oxidation of exo-methylenetetrahydrofurans

The synthesis of various β,β-disubstituted-α-methylene-γ-butyrolactones was carried out from the corresponding methylenetetrahydrofuran derivatives by using PCC/Ac2O or Jones oxidation conditions.