Syntheses of dipeptides containing (1R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2(S)-carboxylic acid (4), (1R,5S)-spiro[3-azabicyclo[3.1.0]hexane-6,1′-cyclopropane]- 2(S)-carboxylic acid (5) and (1S,5R)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2(S)-carbox

Versatile syntheses of dipeptides that incorporate the 3-azabicyclo[3.1.0]hexane system are described.

Figure optionsDownload as PowerPoint slide