Synthesis of 1,2,3,4-tetrasubstituted pyrrole derivatives via the palladium-catalyzed reaction of 1,3-diketones with methyleneaziridines

The palladium-catalyzed reaction of 1,3-diketones 2 with methyleneaziridines 1 produced the corresponding 1,2,3,4-tetrasubstituted pyrroles 3 in good to high yields.

The palladium-catalyzed reaction of 1,3-diketones with methyleneaziridines produced the corresponding 1,2,3,4-tetrasubstituted pyrroles in good to high yields.