کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5277592 | 1385584 | 2008 | 4 صفحه PDF | دانلود رایگان |

A new type of atropisomeric bisaminophosphine ligands 2 with a bridge across the 5,5â²-position of biphenyl has been developed. The axial chirality of this type of ligands can be retained by macro-ring strain produced from 5,5â²-linkage of biphenyl even without 6,6â²-substituents on biphenyls. The ligand (R)-2a showed high catalytic activities and enantioselectivities (up to 95.3% ee and quantitative yields) for Rh(I)-catalyzed asymmetric hydrogenation of a variety of methyl (Z)-2-acetamido-3-arylacrylates.
A new type of atropisomeric bisphosphine ligands 2 with a bridge across the 5,5â²-position of biphenyl has been developed. The axial chirality of this type of ligands can be retained by macro-ring strain produced from 5,5â²-linkage of biphenyl even without 6,6â²-substituents on biphenyls. The ligand (R)-2a showed high catalytic activities and enantioselectivities (up to 95.3% ee and quantitative yields) for Rh(I)-catalyzed asymmetric hydrogenation of a variety of methyl (Z)-2-acetamido-3-arylacrylates.
Journal: Tetrahedron Letters - Volume 49, Issue 26, 23 June 2008, Pages 4106-4109