کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5277823 | 1385589 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Tonkinensines A and B, two novel alkaloids from Sophora tonkinensis
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Tonkinensines A and B, two novel alkaloids from Sophora tonkinensis Tonkinensines A and B, two novel alkaloids from Sophora tonkinensis](/preview/png/5277823.png)
چکیده انگلیسی
Tonkinensines A (1) and B (2), two novel cytisine-type alkaloids that feature the skeleton with a linkage to pterocarpan, were isolated from the roots of Sophora tonkinensis. Their structures and absolute configurations were elucidated by spectroscopic methods, especially X-ray crystal diffraction and CD spectral analysis. The proposed biosynthetic pathway was also discussed. Both 1 and 2 were tested in HeLa and MDA-MB-231 tumor cell lines, and compound 2 showed moderate cytotoxic activity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 49, Issue 23, 2 June 2008, Pages 3797-3801
Journal: Tetrahedron Letters - Volume 49, Issue 23, 2 June 2008, Pages 3797-3801
نویسندگان
Xing-Nuo Li, Zhi-Qiang Lu, Song Qin, Hai-Xia Yan, Min Yang, Shu-Hong Guan, Xuan Liu, Hui-Ming Hua, Li-Jun Wu, De-An Guo,