Straightforward synthesis of 1,6-dioxaspiro[4.4]nonanes

Diols 2, easily prepared by a DTBB-catalysed lithiation of the dithioether 1 in the presence of different carbonyl compounds, react with ozone in dichloromethane at −78 °C leading, after treatment with thiourea at 20 °C, to the corresponding substituted 1,6-dioxaspiro[4.4]nonanes 3.

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