Radical cyclizations in 1,4-dimethylpiperazine

N-Allylic or N-vinylic α,α,α-trichloroacetamides, upon heating in 1,4-dimethylpiperazine, undergo radical cyclization to give the corresponding γ-lactams.

N-Allylic or N-vinylic α,α,α-trichloroacetamides, upon heating in 1,4-dimethylpiperazine, undergo radical cyclization to give the corresponding γ-lactams.