کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5278731 1385610 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer
چکیده انگلیسی

Dicyclohexylcarbodiimide-promoted self-condensation of 2,3:4,5-di-O-isopropylidene-d-galactonic acid (3) led to the macrocyclic oligomeric cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)2] (4) and cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)3] (5), having, respectively, 14- and 21-membered rings. The macrocycles 4 and 5 were also synthesized by cyclization of the respective linear dimer 11 and trimer 14 ω-hydroxy acids precursors prepared by stepwise additions of 3. Compounds 4 and 5 are biomaterials that may be described as macrolactone-cyclodextrins.

Macrocyclic lactones 4 and 5 were prepared by cyclization of the respective dimer and trimer linear precursors obtained by self-condensation of the d-galactonic acid derivative 3.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 50, Issue 40, 7 October 2009, Pages 5677-5680
نویسندگان
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