Stereoselective synthesis of (22Z)-25-hydroxyvitamin D2 and (22Z)-1α,25-dihydroxyvitamin D2

Two new vitamin D2 analogues, (22Z)-25-(OH)-D2 and (22Z)-1α,25-(OH)2-D2, were serendipitously synthesized from vitamin D2 and using the Julia-Kocienski olefination.