کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5279581 1385628 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A new convenient synthesis of N-acyl-2-(dimethoxyphosphoryl)glycinates
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
A new convenient synthesis of N-acyl-2-(dimethoxyphosphoryl)glycinates
چکیده انگلیسی

Easily accessible N-acyl-2-triphenylphosphonioglycinate tetrafluoroborates react smoothly with trimethylphosphite in the presence of methyltriphenylphosphonium iodide to give N-acyl-2-(dimethoxyphosphoryl)glycinates in good or very good yields. The dimethoxyphosphorylglycinates may be isolated by column chromatography, or used directly for the Wadsworth-Emmons synthesis of α,β-dehydro-α-amino acids in a one-pot procedure without purification.

N-Acyl-2-triphenylphosphonioglycinate tetrafluoroborates react smoothly with trimethylphosphite in the presence of methyltriphenylphosphonium iodide to give N-acyl-2-(dimethoxyphosphoryl)glycinates in good or very good yields.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 47, Issue 20, 15 May 2006, Pages 3439-3442
نویسندگان
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