کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5279801 | 1385633 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Palladium-catalyzed cross-coupling of 2-haloselenophene with terminal alkynes in the absence of additive
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Palladium-catalyzed cross-coupling of 2-haloselenophene with terminal alkynes in the absence of additive Palladium-catalyzed cross-coupling of 2-haloselenophene with terminal alkynes in the absence of additive](/preview/png/5279801.png)
چکیده انگلیسی
We present herein our results of the Sonogashira coupling reaction of 2-haloselenophenes with terminal alkynes catalyzed by PdCl2(PPh3)2, under co-catalyst free conditions and establish a new procedure to prepare (2-alkynyl)-selenophenes in good yields. The reaction proceeded cleanly under mild reaction conditions and was performed with propargylic alcohols, protected propargylic alcohols, propargylic amines, as well as alkyl, and aryl alkynes, in the presence of PdCl2(PPh3)2, Et3N, DMF, and in the absence of any supplementary additives. In addition, by this protocol (2,5-bis-alkynyl)-selenophenes were also obtained, in a one pot procedure, using 2,5-bis-iodoselenofene with an excess of terminal alkynes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 47, Issue 13, 27 March 2006, Pages 2179-2182
Journal: Tetrahedron Letters - Volume 47, Issue 13, 27 March 2006, Pages 2179-2182
نویسندگان
Olga Soares do Rêgo Barros, Alexandre Favero, Cristina W. Nogueira, Paulo H. Menezes, Gilson Zeni,