کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5281073 | 1385661 | 2010 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Facile route to benzils from aldehydes via NHC-catalyzed benzoin condensation under metal-free conditions Facile route to benzils from aldehydes via NHC-catalyzed benzoin condensation under metal-free conditions](/preview/png/5281073.png)
A simple and efficient one-pot procedure for the synthesis of α-diketones from aldehydes via benzoin condensation under the influence of a catalytic amount of azolium salt combined with DBU has been developed. Thus, aldehyde was allowed to react with the azolium salt/DBU catalytic system at room temperature, and then the reaction mixture was heated to 70 °C under air atmosphere to afford the corresponding 1,2-diketone in good yield. This would be an efficient alternative method of synthesizing α-diketones from aldehydes under metal-free conditions.
A simple and efficient one-pot procedure for the synthesis of α-diketones from aldehydes via benzoin condensation under the influence of a catalytic amount of azolium salt combined with DBU has been developed.
Journal: Tetrahedron Letters - Volume 51, Issue 13, 31 March 2010, Pages 1786-1789