A highly selective Ir-catalyzed borylation of 2-substituted indoles: a new access to 2,7- and 2,4,7-substituted indoles

The iridium-catalyzed borylation of 2-substituted indoles has been investigated. Direct CH-activation is observed highly selective at the 7-position of the indole. The scope and limitation of the mono- and di-borylation reaction are presented.