Cupric chloride promoted regioselective C-allylation of enaminones

Regioselective allylation of enaminones using CuCl2 as the catalyst to give C-allylated products is reported for the first time. The C-allylated products undergo hydrolysis followed by a rearrangement yielding β-keto allyl enamides in excellent yields.

Regioselective C-allylation of enaminones catalysed by cupric chloride to give β-keto allyl enamides is reported.