A short synthesis of 3,6-disubstituted N-2-thienyl/aryl-indoles

Various 3,6-disubstituted N-2-thienyl/aryl-indoles were prepared by a short synthetic strategy involving reaction of substituted 2,4-difluoro/dichloro-styrene epoxide with substituted 2-formylaminothiophene/N-formylaniline in the presence of a base followed by treatment with an acid.