Studies toward the total synthesis of cyclodidemniserinol trisulfate. Part I: 3,5,7-Trisubstituted 6,8-dioxabicyclo [3.2.1] octane core structure construction via a convergent and a linear stereoselective synthesis

The 3,5,7-trisubstituted dioxabicyclic portion of cyclodidemniserinol trisulfate was synthesized by employing intramolecular ketal formation strategy via a convergent and a linear stereoselective synthesis approach, respectively.