کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5283801 1385723 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Regioselective Barbier reactions of 2-bromomethylcyclohexenone
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Regioselective Barbier reactions of 2-bromomethylcyclohexenone
چکیده انگلیسی
Although the addition of crotyl or prenyl organometallic reagents has certainly found application in organic synthesis, the use of other non-symmetric allylic organometallic reagents has not received much attention. In part this is due to potential problems in controlling the regioselectivity of the addition products. We have noted that the tin and zinc reagents derived from 2-bromomethylcyclohexenone afford the complementary α and γ addition products, respectively. These conditions work for the reaction with a range of aldehydes, affording the products in good to modest yield.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 48, Issue 22, 28 May 2007, Pages 3819-3822
نویسندگان
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