Synthesis of bhimamycin B based on oxidative rearrangement of 4-acetylnaphtho[1,2-b]furan-5-ol to naphtho[2,3-c]furan-4,9-dione

The first total synthesis of bhimamycin B was achieved by oxidative skeletal rearrangement of 4-acetylnaphtho[1,2-b]furan-5-ol with PhI(OAc)2.