کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
528582 869584 2009 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Linguistic recognition system for identification of some possible genes mediating the development of lung adenocarcinoma
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر چشم انداز کامپیوتر و تشخیص الگو
پیش نمایش صفحه اول مقاله
Linguistic recognition system for identification of some possible genes mediating the development of lung adenocarcinoma
چکیده انگلیسی

In the present article, we develop a linguistic recognition system for identification of some possible genes mediating the development of human lung adenocarcinoma. The methodology involves dimensionality reduction, classifying the genes through incorporation of the notion of linguistic fuzzy sets low, medium and high, and finally selection of some possible genes obtained by a rule generation/grouping technique. The system has been successfully applied on two microarray gene expression data sets. The results are appropriately validated by some earlier investigations, gene expression profiles and t-test. The proposed methodology has been able to find more true positives than an existing one in identifying responsible genes. Moreover, we have found some new genes that may have role in mediating the development of lung adenocarcinoma.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Information Fusion - Volume 10, Issue 3, July 2009, Pages 260–269
نویسندگان
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