Utility of 4,6-dichloro-2-(methylthio)-5-nitropyrimidine. Part 3: Regioselective solid-phase synthesis of a 2,6,8,9-tetrasubstituted purine library

A fully regiocontrolled synthesis of a 2,6,8,9-tetrasubstituted purine library was performed through on-resin elaboration of 4,6-dichloro-2-(methylthio)-5-nitropyrimidine.